Hydrochloric Acid → HCID 66876955, compound

Participants

Reaction Steps

4-[3-(4-Methyl-pyridin-2-yloxy)-benzylidene]-piperidine-1-carboxylic acid tert-butyl ester (1.15 g, 2.9 mmol) from Step 4 was dissolved in DCM (10 mL) and treated with HCl in dioxane (4.34 mL, 4.0 M, 17.3 mmol). After 16 hours the reaction was concentrated in vacuo to provide the title compound as a white solid (1.6 g).

Provenance & Evidence