反应详情

Amorphous mupirocin calcium (5.00 g, 4.80 mmole) was dissolved in methanol (15 ml) and stirred to give a clear solution. Water (10 ml) was added to the solution. Methanol from the solution was evaporated at reduced pressure to give a final volume of 7 ml. The mupirocin calcium solution was allowed to crystallize for 60 h at 5° C. The crystalline product was filtered and washed with water (5 ml). The product was dried at 30° C. for 12 h.

1. customto give a clear solution
2. customMethanol from the solution was evaporated at reduced pressure
3. customto give a final volume of 7 ml
4. customto crystallize for 60 h at 5° C
5. filtrationThe crystalline product was filtered
6. washwashed with water (5 ml)
7. customThe product was dried at 30° C. for 12 h.