Water → Mupirocin Calcium

Participants

Reaction Steps

Amorphous mupirocin calcium (5.00 g, 4.80 mmole) was dissolved in methanol (15 ml) and stirred to give a clear solution. Water (10 ml) was added to the solution. Methanol from the solution was evaporated at reduced pressure to give a final volume of 7 ml. The mupirocin calcium solution was allowed to crystallize for 60 h at 5° C. The crystalline product was filtered and washed with water (5 ml). The product was dried at 30° C. for 12 h.

Provenance & Evidence