HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 66876197, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 66875433 | HCID 66875433 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66876197 | HCID 66876197 | — |
Reaction Steps
A solution of tert-butyl-4-(3-(5-fluoropyridin-2-yloxy)benzylidene)piperidine-1-carboxylate (0.274 g) in dichloromethane (2.5 mL, 0.28 M) was treated with trifluoroacetic acid (2.5 mL). The reaction was allowed to stir for 3 hours, then concentrated to an oil. The oil was used without purification. 0.466 g, quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044052B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-c6a68c454f9e45e79521cb248d5453c9 |
| Source note | uspto-grants-2011_10 |