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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1666542Generated: November 1, 2026

5-Bromo-2-chloropyrimidine → tert-Butyl 3-[(5-bromopyrimidin-2-yl)oxy]pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/1666542

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant1-Boc-3-pyrrolidinolHCID 4416939—
Producttert-Butyl 3-[(5-bromopyrimidin-2-yl)oxy]pyrrolidine-1-carboxylateHCID 23115998—

Reaction Steps

According to the same method as in Example 1-1) but using 1-t-butoxycarbonyl-3-hydroxypyrrolidine and 2-chloro-5-bromopyrimidine, the entitled compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08044070B2
Source datasetuspto-grants-2011_10
ORD IDord-26981281c59e4c128ee79467f2cee48a
Source noteuspto-grants-2011_10