HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenylboronic acid → Benzonitrile, 4-[5-[(1-cyclopentyl-4-piperidinyl)oxy]pyrazinyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Reactant | Tert-butyl 4-(5-bromopyrazin-2-yloxy)piperidine-1-carboxylate | HCID 58456669 | — |
| Product | Benzonitrile, 4-[5-[(1-cyclopentyl-4-piperidinyl)oxy]pyrazinyl]- | HCID 11428018 | — |
Reaction Steps
According to the same method as in Example 1-2), 3), 4) but using 2-(1-t-butoxycabonylpiperidin-4-yloxy)-5-bromopyrazine and 4-cyanophenylboronic acid, the entitled compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044070B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-81a9130555c840deb28b314dc550ff64 |
| Source note | uspto-grants-2011_10 |