反应详情

温度

5 °C

Pseudomonic acid (10 g) was suspended in water (26 ml). Calcium oxide (0.58 g) was added to the suspension. The mixture was stirred for one hour, and filtered. The mixture was cooled to 5° C. After standing for 15 h, the crystalline product was filtered and washed with cooled water (10 ml) and dried in an air circulated oven at room temperature. Mupirocin calcium dihydrate (9.4 g, 87%) was obtained.

1. filtrationfiltered
2. waitAfter standing for 15 h
3. filtrationthe crystalline product was filtered
4. washwashed with cooled water (10 ml)
5. customdried in an air
6. customat room temperature