反应详情

26.8 g (0.5 mol) of ammonium chloride were introduced into a 500 ml stirred reactor fitted with nitrogen inlet and separate feed device and suspended in 200 ml of methanol. Over the course of 30 minutes 76.1 g (0.5 mol) of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) were added, where upon the reaction mixture was solubilized. The mixture was stirred for a further three hours and then the solvent was evaporated and the remaining solid dried in vacuo.

1. customfitted with nitrogen inlet
2. customseparate feed device
3. stirringThe mixture was stirred for a further three hours
4. customthe solvent was evaporated
5. customthe remaining solid dried in vacuo