Oxalic Acid → HCID 21071614, compound

HRID 1666822Notes

Reaction equation

HRID 1666822 reaction equation
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]2[C:12](=[CH:13][CH:14]=1)[C:8]([CH2:9][CH2:10][NH2:11])=[CH:7][NH:6]2.CC(C)=O.CCOCC.[C:26]([OH:31])(=[O:30])[C:27]([OH:29])=[O:28]>CC(C)=O>[C:26]([OH:31])(=[O:30])[C:27]([OH:29])=[O:28].[F:16][C:2]([F:1])([F:15])[C:3]1[CH:4]=[C:5]2[C:12](=[CH:13][CH:14]=1)[C:8]([CH2:9][CH2:10][NH2:11])=[CH:7][NH:6]2

Participants

5

Reactant 3

HCID 971Oxalic AcidHCID 18317967HCID 18317967, compoundHCID 21584533Acetone diethylether

Product 1

HCID 21071614HCID 21071614, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Add 6-trifluoromethyltryptamine to 1:1 acetone/Et2O. Add dropwise of oxalic acid (1.2 eq.) in acetone to give a solid. Collect the solid by filtration and dry overnight in the vacuum oven to obtain the title compound: MS (ES+): m/z 212 (M−NH2)+; (ES−): m/z 227 (M−H)−.

Workup

  1. customto give a solid
  2. customCollect the solid
  3. filtrationby filtration
  4. customdry overnight in the vacuum oven

Sources & evidence

ORD record
ord-aa2e92ef5cb240b894f4d812a5011db8
Source dataset
uspto-grants-2011_10
Patent number
US08044090B2

Reaction notes

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