1-(Diphenylmethyl)-4-piperidinamine → HCID 67444020, compound

Participants

Reaction Steps

The title compound was prepared as described in Example 28B, reacting 2-(2-oxo-3,3-diphenylpiperidin-1-yl)acetic acid (Example 68E) with 1-benzhydrylpiperidin-4-amine (Example 48A). 1H NMR (300 MHz, CDCl3) δ ppm 7.14-7.43 (m, 20H), 6.58 (d, J=8.1 Hz, 1H), 4.24 (s, 1H), 4.01 (s, 2H), 3.72-3.84 (m, 1H), 3.53 (t, J=6.4 Hz, 2H), 2.70-2.77 (m, 2H), 2.58-2.63 (m, 2H), 1.97-2.08 (m, 2H), 1.76-1.91 (m, 5H), 1.41-1.50 (m, 1H); MS (ESI+) m/z 558 (M+H)+.

Provenance & Evidence