1,4-Dioxane hydrochloride → HCID 67359480, compound

Participants

Reaction Steps

A solution of product from Example 185A (0.32 g, 0.9 mmol) in methanol (10 mL) was treated with 4 N HCl/dioxane (2 mL) for 2 hours at room temperature. The reaction mixture was concentrated to yield the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 7.60 (m, 3H), 6.99 (m, 1H), 3.93 (m, 1H), 3.64 (dd, 2H), 2.69 (m, 1H), 2.45 (m, 2H), 2.26 (m, 1H), 1.99 (m, 1H), 1.60 (m, 1H); MS (ESI+) m/z 244 (M+H)+.

Provenance & Evidence