Hydrochloric Acid → (3-Aminomethyl-phenyl)-(2-morpholin-4-yl-ethyl)-amine hydrochloride

Participants

Reaction Steps

A mixture of [3-(2-morpholin-4-yl-ethylamino)-benzyl]-carbamic acid isopropyl ester (200 mg, 0.596 mmol), methanol (4 mL) and 4.89N isopropanolic hydrochloric acid (2.4 mL) was stirred at room temperature overnight. The reaction was concentrated and dried to yield (3-aminomethyl-phenyl)-(2-morpholin-4-yl-ethyl)-amine hydrochloride (212 mg) as an orange solid. m/z (M+1) 236.04.

Provenance & Evidence