HCID 67443655, compound → HCID 67446119, compound

HRID 1667608Notes

Reaction equation

HRID 1667608 reaction equation
[C:1]([O:5][C:6]([CH2:8][C:9]1[CH:39]=[CH:38][C:12]([O:13][CH:14]([C:25]2[CH:30]=[CH:29][C:28]([O:31][CH:32]([CH3:34])[CH3:33])=[C:27]([O:35][CH2:36][CH3:37])[CH:26]=2)[C:15]([O:17]CC2C=CC=CC=2)=[O:16])=[CH:11][CH:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6]([CH2:8][C:9]1[CH:39]=[CH:38][C:12]([O:13][CH:14]([C:25]2[CH:30]=[CH:29][C:28]([O:31][CH:32]([CH3:34])[CH3:33])=[C:27]([O:35][CH2:36][CH3:37])[CH:26]=2)[C:15]([OH:17])=[O:16])=[CH:11][CH:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 67443655HCID 67443655, compound

Product 1

HCID 67446119HCID 67446119, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A mixture of 13B (85 mg, 0.15 mmol) and Pd/C (cat.) was hydrogenated at 40 psi overnight. The reaction was filtered and concentrated to provide 13C (39 mg, 99%). LC-MS: 482.37 (M+Na)+.

Workup

  1. customwas hydrogenated at 40 psi overnight
  2. filtrationThe reaction was filtered
  3. concentrationconcentrated
  4. customto provide 13C (39 mg, 99%)

Sources & evidence

ORD record
ord-274d211d12ae4e7cb81b177c0650c59a
Source dataset
uspto-grants-2011_10
Patent number
US08044242B2

Reaction notes

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