HRID1667618

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc([C@@H](C)N2CCC[C@H]2c2ccnc(N3CCc4ccccc43)c2)cc1

HCID58111948

未命名化合物

PRODUCTS

生成物

结构：c1ccc2c(c1)CCN2c1cc([C@@H]2CCCN2)ccn1

HCID58111932

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

A solution of (1-(4-{(S)-1-[(R)-1-(4-Methoxy-phenyl)-ethyl]-pyrrolidin-2-yl}-pyridin-2-yl)-2,3-dihydro-1H-indole (140 mg, 0.35 mmol) in TFA (10 mL) is heated in microwave at 100° C. for 30 min and concentrated down to give crude 1-((S)-4-pyrrolidin-2-yl-pyridin-2-yl)-2,3-dihydro-1H-indole (6), which is used in next step without further purification.

WORKUP

后处理

concentrationconcentrated down