HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668282Generated: November 1, 2026
Diisopropylethylamine → HCID 24946567, compound
https://huagongshe.com/reaction/1668282
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | (Cyanomethyl)trimethylphosphanium iodide | HCID 10514344 | — |
| Reactant | HCID 24946392 | HCID 24946392 | — |
| Solvent | Propionitrile | HCID 7854 | — |
| Product | HCID 24946567 | HCID 24946567 | 69.1% |
Reaction Steps
Following the procedure as described in example a solution of 1-[2-(3,5-dimethylphenyl)-1-furan-2-yl-ethyl]-3-(2-hydroxy-ethyl)-thiourea (0.46 g) and diisopropyethylamine (0.26 g) in propionitrile (20 ml) was treated with cyanomethyl trimethylphosphonium iodide (0.44 g) and heated for 16 h at a temperature of 90° C. Work-up yielded the title compound (0.30 g, 69%) as an amorphous solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07989394B2 |
|---|
| Source dataset | uspto-grants-2011_08 |
|---|
| ORD ID | ord-4a3f3eb29cb9434ab7a79c73b63f651a |
|---|
| Source note | uspto-grants-2011_08 |
|---|
