Dimethylformamide → isopropyl 2-chloro-4-fluoro-5-[3,6-dihydro-5-ethyl-3,4-dimethyl-2,6-dioxo-1(2H)-pyrimidinyl]-benzoate

HRID 166835Notes

Reaction equation

HRID 166835 reaction equation
[CH3:26][O:27][S:28]([O:29][CH3:30])(=[O:31])=[O:32].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH:7]([CH3:8])[CH3:9])[cH:10][c:11](-[n:15]2[c:16](=[O:25])[nH:17][c:18]([CH3:24])[c:19]([CH2:22][CH3:23])[c:20]2=[O:21])[c:12]([F:14])[cH:13]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH:7]([CH3:8])[CH3:9])[cH:10][c:11](-[n:15]2[c:16](=[O:25])[n:17]([CH3:26])[c:18]([CH3:24])[c:19]([CH2:22][CH3:23])[c:20]2=[O:21])[c:12]([F:14])[cH:13]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 6497Dimethyl SulfateHCID 20130627isopropyl 2-chloro-4-fluoro-5-[3,6-dihydro-5-ethyl-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-benzoate

Product 1

HCID 20130665isopropyl 2-chloro-4-fluoro-5-[3,6-dihydro-5-ethyl-3,4-dimethyl-2,6-dioxo-1(2H)-pyrimidinyl]-benzoate

Sources & evidence

ORD record
ord-9ec6a87b6715402db5089728de27ffcd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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