Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Methyl 5-(4-chlorophenyl)-3-(dimethylaminomethyleneamino)thiophene-2-carboxylate | HCID 11544322 | — |
| Reactant | HCID 67361948 | HCID 67361948 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67360824 | HCID 67360824 | 50.6% |
Reaction Steps
A mixture of methyl 5-(4-chlorophenyl)-3-(dimethylaminomethyleneamino)thiophene-2-carboxylate (0.2 g), 2-[4-(N-tert-butyloxycarbonyl-N-methylaminomethyl)phenyl]ethanamine (0.19 g) and ethanol (4 ml) were stirred at 70° C. for 3 hr. The reaction mixture was allowed to cool, ethyl acetate was added, and the precipitate was collected by filtration to give the title compound (160 mg) as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07989445B2 |
|---|
| Source dataset | uspto-grants-2011_08 |
|---|
| ORD ID | ord-979bc0fb3ea54745969745e54c623247 |
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| Source note | uspto-grants-2011_08 |
|---|
