反应详情

A solution of 3-acetyl-7-nitro-2,3,4,5-tetrahydro-1H-3-benzazepine (2.9 g) in HCl (conc) (200 ml) as refluxed for 48 h. Mixture was cooled at 0° C. and neutralised with NaOH (conc.) then was extracted with DCM. The organic layer was collected and the aqueous phase extracted twice with DCM. The combined DCM layers were concentrated to provide the target compound (2.33 g).

1. extractionthen was extracted with DCM
2. customThe organic layer was collected
3. extractionthe aqueous phase extracted twice with DCM
4. concentrationThe combined DCM layers were concentrated