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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668607Generated: October 29, 2026

5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → 7-(3-{[4-Methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-2-propyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine hydrochloride

https://huagongshe.com/reaction/1668607

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinolineHCID 25105050—
Reactant2-Propyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepineHCID 59150503—
Product7-(3-{[4-Methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-2-propyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine hydrochlorideHCID 67357962—

Reaction Steps

The title compound was prepared in analogy to General Procedure 1 from 2-propyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (87 μmol) and 5-{5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline and was obtained as a colourless solid (55 μmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989444B2
Source datasetuspto-grants-2011_08
ORD IDord-b021d0ffe14b408da20b2299463d97c5
Source noteuspto-grants-2011_08