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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668622Generated: October 30, 2026

3-{5-[(3-Chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine → 2-Ethyl-7-(3-{[4-methyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine hydrochloride

https://huagongshe.com/reaction/1668622

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-{5-[(3-Chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}pyridineHCID 53417310—
Reactant2-ethyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepineHCID 59150491—
Product2-Ethyl-7-(3-{[4-methyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine hydrochlorideHCID 67358191—

Reaction Steps

The title compound was prepared in analogy to General Procedure 1 from 2-ethyl-6,7,8,9-tetrahydro-5H-[1,3]oxazolo[4,5-h][3]benzazepine (0.25 mmol) and 3-{5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine and was obtained as a faint yellow slightly hygroscopic solid (0.12 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989444B2
Source datasetuspto-grants-2011_08
ORD IDord-fe682273aba94b8f84aa9c95c6f0f5d0
Source noteuspto-grants-2011_08