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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668630Generated: October 29, 2026

3-[(3-Chloropropyl)thio]-4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazole → 2-ethyl-7-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-6,7,8,9-tetrahydro-5H-[1,3]thiazolo[4,5-h][3]benzazepine hydrochloride

https://huagongshe.com/reaction/1668630

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(3-Chloropropyl)thio]-4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazoleHCID 44627994—
Reactant2-ethyl-6,7,8,9-tetrahydro-5H-[1,3]thiazolo[4,5-h][3]benzazepineHCID 59150514—
Product2-ethyl-7-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-6,7,8,9-tetrahydro-5H-[1,3]thiazolo[4,5-h][3]benzazepine hydrochlorideHCID 67358171—

Reaction Steps

The title compound was prepared in analogy to General Procedure 1 from 2-ethyl-6,7,8,9-tetrahydro-5H-[1,3]thiazolo[4,5-h][3]benzazepine (0.14 mmol) and 3-[(3-chloropropyl)thio]-4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazole (0.16 mmol) and was obtained as a colourless slightly hygroscopic solid (13 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989444B2
Source datasetuspto-grants-2011_08
ORD IDord-8e5fddbc2bff4beca31203dd1a4cb350
Source noteuspto-grants-2011_08