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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668643Generated: October 30, 2026

5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → 2-(1-methylethyl)-7-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one hydrochloride

https://huagongshe.com/reaction/1668643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinolineHCID 25105050—
ReactantHCID 59150504HCID 59150504—
Product2-(1-methylethyl)-7-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one hydrochlorideHCID 67358126—

Reaction Steps

The title compound was prepared in analogy to General Procedure 1 from 2-(1-methylethyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one (80 mg) and 5-{5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (130 mg) and was obtained as a colourless slightly hygroscopic solid (120 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989444B2
Source datasetuspto-grants-2011_08
ORD IDord-417183f17d7b4340856981822e073709
Source noteuspto-grants-2011_08