HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline → 2-(1-methylethyl)-7-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl)-2-methylquinoline | HCID 25105050 | — |
| Reactant | HCID 59150504 | HCID 59150504 | — |
| Product | 2-(1-methylethyl)-7-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one hydrochloride | HCID 67358126 | — |
Reaction Steps
The title compound was prepared in analogy to General Procedure 1 from 2-(1-methylethyl)-3,5,6,7,8,9-hexahydroazepino[4,5-f]isoindol-1(2H)-one (80 mg) and 5-{5-[(3-chloropropyl)thio]-4-methyl-4H-1,2,4-triazol-3-yl}-2-methylquinoline (130 mg) and was obtained as a colourless slightly hygroscopic solid (120 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989444B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-417183f17d7b4340856981822e073709 |
| Source note | uspto-grants-2011_08 |