HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 57825009, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | 3-Bromo-5-fluorobenzonitrile | HCID 2783330 | — |
| Product | HCID 57825009 | HCID 57825009 | 44% |
Reaction Steps
In analogy to the procedure described in WO2007060448, the reaction of 3-bromo-5-fluorobenzonitrile with ethanol using sodium bis(trimethylsilyl)amide as the base yielded the title compound as a light brown oil (yield: 44% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989449B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-f353914028b74196adb91a967c5e4f17 |
| Source note | uspto-grants-2011_08 |