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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668779Generated: October 26, 2026

N-Methyl-4-anisidine → (2-Chloro-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamine

https://huagongshe.com/reaction/1668779

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant2,4-Dichloro-6-nitroquinazolineHCID 12703366—
Product(2-Chloro-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamineHCID 11609884—

Reaction Steps

The title compound was prepared from 2,4-dichloro-6-nitro-quinazoline and 4-methoxy-N-methylaniline by a procedure similar to example 10. 1H NMR (CDCl3): 8.31 (dd, J=9.6, 3.6, 1H), 7.78 (d, J=9.3, 1H), 7.73 (d, J=2.4, 1H), 7.21 (m, 2H), 7.06 (m, 2H), 3.90 (s, 3H), 3.69 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989462B2
Source datasetuspto-grants-2011_08
ORD IDord-2b6036b36a004006804a9fd7752fd82a
Source noteuspto-grants-2011_08