HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → (2-Methylamino-quinazolin-4-yl)-(4-dimethylaminophenyl)-methylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | (2-Chloro-quinazolin-4-yl)-(4-dimethylaminophenyl)-methylamine | HCID 11688214 | — |
| Product | (2-Methylamino-quinazolin-4-yl)-(4-dimethylaminophenyl)-methylamine | HCID 11638105 | — |
Reaction Steps
The title compound was prepared from (2-chloro-quinazolin-4-yl)-(4-dimethylaminophenyl)-methylamine and methyl amine by a procedure similar to example 14. 1H NMR (CDCl3): 7.42-7.42 (m, 1H), 7.34 (ddd, J=8.1, 6.9, 4.0, 1H), 7.04 (m, 2H), 6.94 (m, 1H), 6.63-6.71 (m, 3H), 5.13 (s, broad, 1H), 3.49 (s, 3H), 3.10 (d, J=4.8, 3H), 2.97 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989462B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-808f4526e0fb46b8b67e9ff6fd6d180e |
| Source note | uspto-grants-2011_08 |