HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → (2-Methylamino-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | (2-Chloro-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamine | HCID 11609884 | — |
| Product | (2-Methylamino-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamine | HCID 11595263 | — |
Reaction Steps
The title compound was prepared from (2-chloro-6-nitro-quinazolin-4-yl)-(4-methoxyphenyl)-methylamine and methyl amine by a procedure similar to example 14. 1H NMR (CDCl3): 8.11 (dd, J=9.3, 8.0, 1H), 7.73 (d, J=2.4, 1H), 7.33 (m, 1H), 7.15 (m, 2H), 6.98 (m, 2H), 5.29 (s, broad, 1H), 3.86 (s, 3H), 3.55 (s, broad, 3H), 3.14 (d, J=4.8, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989462B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-60f7507c09a84955a0a0c11af6c6ba35 |
| Source note | uspto-grants-2011_08 |