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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1668785Generated: October 26, 2026

Methylamine → (2-Methylamino-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamine

https://huagongshe.com/reaction/1668785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant(2-Chloro-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamineHCID 11609884—
Product(2-Methylamino-6-nitroquinazolin-4-yl)-(4-methoxyphenyl)-methylamineHCID 11595263—

Reaction Steps

The title compound was prepared from (2-chloro-6-nitro-quinazolin-4-yl)-(4-methoxyphenyl)-methylamine and methyl amine by a procedure similar to example 14. 1H NMR (CDCl3): 8.11 (dd, J=9.3, 8.0, 1H), 7.73 (d, J=2.4, 1H), 7.33 (m, 1H), 7.15 (m, 2H), 6.98 (m, 2H), 5.29 (s, broad, 1H), 3.86 (s, 3H), 3.55 (s, broad, 3H), 3.14 (d, J=4.8, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989462B2
Source datasetuspto-grants-2011_08
ORD IDord-60f7507c09a84955a0a0c11af6c6ba35
Source noteuspto-grants-2011_08