2,3-Dihydroxybutanedioic Acid → 3-(3-Ethoxycarbonylmethoxy-4-methyl-phenyl)-piperidine-1-carboxylic acid 4-trifluoromethyl-benzyl ester
Reaction equation
[C:1]([OH:2])(=[O:3])[CH:4]([CH:5]([C:6]([OH:7])=[O:8])[OH:9])[OH:10].[CH2:11]([CH3:12])[O:13][C:14]([CH2:15][O:16][c:17]1[c:18]([CH3:29])[cH:19][cH:20][c:21]([CH:23]2[CH2:24][NH:25][CH2:26][CH2:27][CH2:28]2)[cH:22]1)=[O:30].[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[F:31][C:32]([c:33]1[cH:34][cH:35][c:36]([CH2:37][O:38][C:39](=[O:40])[n:41]2[cH:42][cH:43][n:44][cH:45]2)[cH:46][cH:47]1)([F:48])[F:49]>>[CH2:11]([CH3:12])[O:13][C:14]([CH2:15][O:16][c:17]1[c:18]([CH3:29])[cH:19][cH:20][c:21]([CH:23]2[CH2:24][N:25]([C:39]([O:38][CH2:37][c:36]3[cH:35][cH:34][c:33]([C:32]([F:31])([F:48])[F:49])[cH:47][cH:46]3)=[O:40])[CH2:26][CH2:27][CH2:28]2)[cH:22]1)=[O:30]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ea97d7128b5f4b75a1574c88339f4a4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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