HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → HCID 178487732, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 2-(4-Fluorobenzamido)-4-methoxy-3-methylbenzoic acid | HCID 59165475 | — |
| Product | HCID 178487732 | HCID 178487732 | 83% |
Reaction Steps
2-(4-Fluoro-benzoylamino)-4-methoxy-3-methyl-benzoic acid (66) (830 mg, 2.7 mmol) was heated to 150° C. in formamide (20 ml) for 4 h. The excess formamide was removed by distillation. Water was added and the precipitated product was filtered of to give pure title compound (642 mg, 83%). MS (M+H+) 285.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989471B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-986032bd2a254d77b5f809474558bdb0 |
| Source note | uspto-grants-2011_08 |