Lactide, L- → HCID 131729080, compound

Participants

Reaction Steps

According to the molar ratio of L-Lactide: 3-[4-(benzyloxycarbonylamino) butyl]-morpholine-2,5-dione monomer=1: 19, 42.75 g L-Lactide and 5 g 3-[4-(benzyloxycarbonylamino) butyl]-morpholine-2,5-dione monomer are weighed and put into ampule, and then inject 5 ml stannous octoate chloroform solution of 30 mg/ml. After volatilization of the chloroform under vacuum, the ampule is sealed with alcohol blast burner. Finally, the sealed ampule is put into oil-bath of 90-140° C. for 12-72 h to obtain poly (glycolic acid-Nε-benzyloxycarbonyl-L-lysine-L-lactic acid).

Provenance & Evidence