HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Bis(bromomethyl)-4-nitrobenzene → 4-Aminoindolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Bis(bromomethyl)-4-nitrobenzene | HCID 10852360 | — |
| Reactant | 4-Nitro-1,3-dihydro-2H-indol-2-one | HCID 21677874 | — |
| Product | 4-Aminoindolin-2-one | HCID 12237472 | — |
Reaction Steps
Essentially following the procedures described in Intermediate 4, but using 4-nitro-1,3-dihydro-2H-indol-2-one from Step A in place of 5-nitro-1′-{[2-(trimethylsilyl)ethoxy]methyl}-1,3-dihydrospiro[indene-2,3′-pyrrolo[2,3-b]pyridin]-2′(1′H)-one, the title compound was obtained. MS: m/z=149(M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989624B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-746564d338904342a9e423c0a12a77e6 |
| Source note | uspto-grants-2011_08 |