4-Aminotetrahydropyran → HCID 44217830, compound

HRID 1669704Notes

Reaction equation

HRID 1669704 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2I)[N:3]=1.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[NH2:21][CH:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1>>[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH:20][C:2]2[CH:11]=[CH:10][C:9]3[C:8]([NH:21][CH:22]4[CH2:27][CH2:26][O:25][CH2:24][CH2:23]4)=[CH:7][CH:6]=[CH:5][C:4]=3[N:3]=2)=[CH:16][CH:15]=1

Participants

4

Reactant 3

HCID 4192234-AminotetrahydropyranHCID 27246835-Methyl-2-furylmethylamineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 44217830HCID 44217830, compound

Procedure

The title compound, MS: m/e=338.4 (M+H+), was prepared in accordance with the general method of example 3 from 2-chloro-5-iodo-quinoline (CAS 455955-26-7), 5-methyl-2-furanmethanamine and 4-amino-tetrahydropyran.

Sources & evidence

ORD record
ord-11c87a6c51804de5a7001b30a376dd05
Source dataset
uspto-grants-2011_08
Patent number
US07989628B2

Reaction notes

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