Tributylvinyltin → (5-Methyl-furan-2-ylmethyl)-(5-vinyl-quinolin-2-yl)-amine

HRID 1669717Notes

Reaction equation

Br[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([NH:12][CH2:13][C:14]1[O:15][C:16]([CH3:19])=[CH:17][CH:18]=1)=[N:7]2.[CH:20]([Sn](CCCC)(CCCC)CCCC)=[CH2:21]>>[CH3:19][C:16]1[O:15][C:14]([CH2:13][NH:12][C:6]2[CH:5]=[CH:4][C:3]3[C:8](=[CH:9][CH:10]=[CH:11][C:2]=3[CH:20]=[CH2:21])[N:7]=2)=[CH:18][CH:17]=1

Participants

Reactant 2

HCID 81998Tributylvinyltin

HCID 67333430(5-Bromo-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine

Product 1

HCID 44218151(5-Methyl-furan-2-ylmethyl)-(5-vinyl-quinolin-2-yl)-amine

Procedure

The title compound, MS: m/e=265.3 (M+H+), was prepared in accordance with the general method of example 22 from (5-bromo-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine and vinyltributyltin.

Sources & evidence

ORD record: ord-d35571973174416db442cb04b7717ec7
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07989628B2

Reaction notes

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