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HRID1669782

反应详情

EQUATION

反应方程式

HRID 1669782 的结构方程式

REACTANTS

反应物

2
结构：CCCOC(=O)/C=C(/C)N
HCID12706963

未命名化合物

结构：COc1ccc(C(=O)C(=Cc2cccc3c(=O)cc(C)oc23)C(C)=O)cc1
HCID67342741

未命名化合物

PRODUCTS

生成物

1
结构：CCCOC(=O)C1=C(C)NC(C)=C(C(=O)c2ccc(OC)cc2)C1c1cccc2c(=O)cc(C)oc12
HCID57503342

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

230 mg (0.63 mmol) of 1-(4-methoxyphenyl)-2-[(2-methyl-4-oxo-4H-chromen-8-yl)methylene]-butane-1,3-dione are heated with 90 mg (0.63 mmol) of n-propyl 3-aminocrotonate in 5 ml of 2-propanol under reflux overnight. The solvent is removed in vacuo, and the residue is purified by preparative HPLC. 74 mg (24% of theory) of the title compound are obtained.

WORKUP

后处理

  1. temperatureunder reflux overnight
  2. customThe solvent is removed in vacuo
  3. customthe residue is purified by preparative HPLC