HCID 57438909, compound → HCID 67342657, compound

Participants

Reaction Steps

3-Methyl-5-[4-(trifluoromethyl)phenyl]isoxazole (1.8 g, 7.92 mmol) is introduced into 20 ml of ethanol, platinum(IV) oxide catalyst (180 mg) is added, and the mixture is then hydrogenated under atmospheric pressure hydrogen for 12 h. The catalyst is filtered off, and the filtrate is concentrated. 1.72 g (94% of theory) of the title compound are obtained as a white solid.

Provenance & Evidence