HRID1670025

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4778242

未命名化合物

结构：CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)O

HCID7018791

Boc-4-chloro-D-phenylalanine

C14H18ClNO4

结构：CC(C)(C)OC(=O)NCC(=O)N(C1CCCCC1)[C@H]1CCNC1

HCID67343482

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)NN1CCC(NC2CCCCC2)CC1

HCID67345059

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure described in Intermediate 129 using (2R)-2-(BOC)amino-3-(4-chlorophenyl)propionic acid and 4-[(cyclohexyl)amino]piperidine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9f15c565369e48e2a12b52c72d969ff7
来源数据集: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07989634B2
来源说明: uspto-grants-2011_08

反应 SMILES

C1([N:7](C(=O)CNC(OC(C)(C)C)=O)[C@H]2CCNC2)CCCCC1.[C:24]([NH:31][C@H:32]([CH2:36][C:37]1[CH:42]=[CH:41][C:40]([Cl:43])=[CH:39][CH:38]=1)[C:33]([OH:35])=O)([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25].[CH:44]1([NH:50][CH:51]2[CH2:56][CH2:55][NH:54][CH2:53][CH2:52]2)[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]1>>[C:24]([NH:31][C@H:32]([CH2:36][C:37]1[CH:42]=[CH:41][C:40]([Cl:43])=[CH:39][CH:38]=1)[C:33]([NH:7][N:54]1[CH2:53][CH2:52][CH:51]([NH:50][CH:44]2[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]2)[CH2:56][CH2:55]1)=[O:35])([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:25]