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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1670025Generated: November 2, 2026

N-cyclohexylpiperidin-4-amine → (2R)-2-(BOC)amino-N-[4-(cyclohexylamino)piperidine-1-yl]-3-(4-chlorophenyl)propionamide

https://huagongshe.com/reaction/1670025

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-cyclohexylpiperidin-4-amineHCID 4778242—
ReactantN-Boc-4-chloro-D-phenylalanineHCID 7018791—
Reactant(3S)-3-{cyclohexyl[(N-BOC)aminoacetyl]amino}pyrrolidineHCID 67343482—
Product(2R)-2-(BOC)amino-N-[4-(cyclohexylamino)piperidine-1-yl]-3-(4-chlorophenyl)propionamideHCID 67345059—

Reaction Steps

The title compound was prepared following the procedure described in Intermediate 129 using (2R)-2-(BOC)amino-3-(4-chlorophenyl)propionic acid and 4-[(cyclohexyl)amino]piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989634B2
Source datasetuspto-grants-2011_08
ORD IDord-9f15c565369e48e2a12b52c72d969ff7
Source noteuspto-grants-2011_08