HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → (3-Iodo-5-methoxy-phenyl)-(4-methyl-piperazin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 3-Iodo-5-methoxybenzoic acid | HCID 57905757 | — |
| Reactant | N-benzyl-3-iodo-5-methoxy-benzamide | HCID 57905830 | — |
| Product | (3-Iodo-5-methoxy-phenyl)-(4-methyl-piperazin-1-yl)-methanone | HCID 57905823 | 80% |
Reaction Steps
The title compound was prepared by the same method as N-benzyl-3-iodo-5-methoxy-benzamide. 4-Methylpiperazine was used instead of benzylamine. Starting with 3.1 g of 3-iodo-5-methoxybenzoic acid, 3.2 g (80% yield) of the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07989454B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-15541b4598884175b2dd85859314d68d |
| Source note | uspto-grants-2011_08 |