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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1670081Generated: November 2, 2026

3-Fluorophenylboronic acid → 5-Benzyloxy-3'-fluoro-biphenyl-3-carboxylic Acid Methyl Ester

https://huagongshe.com/reaction/1670081

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorophenylboronic acidHCID 2733986—
ReactantMethyl 3-benzyloxy-5-(trifluoromethanesulfonyloxy)benzoateHCID 18945283—
Reactant3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-benzoic Acid Methyl EsterHCID 57905932—
Product5-Benzyloxy-3'-fluoro-biphenyl-3-carboxylic Acid Methyl EsterHCID 57905782—

Reaction Steps

The title compound was prepared in the same way as 3-benzo[1,3]dioxol-5-yl-5-benzyloxy-benzoic acid methyl ester (described in Method B, step 3) from 3-benzyloxy-5-trifluoromethanesulfonyloxy-benzoic acid methyl ester and 3-fluorophenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989454B2
Source datasetuspto-grants-2011_08
ORD IDord-9c7f6455e9a1476d9c6d3f9512d5ec47
Source noteuspto-grants-2011_08