Toluene → N-[4-(1-Aminoethyl)-2-fluoro-6-vinylphenyl]methanesulfonamide

HRID 167009Notes

Reaction equation

HRID 167009 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH3:9])[c:10]1[cH:11][c:12]([F:23])[c:13]([NH:18][S:19](=[O:20])(=[O:21])[CH3:22])[c:14]([CH:16]=[CH2:17])[cH:15]1)([CH3:5])([CH3:6])[CH3:24].[CH2:32]([Cl:33])[Cl:34].[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[F:35][C:36]([F:37])([F:38])[C:39]([OH:40])=[O:41]>>[NH2:7][CH:8]([CH3:9])[c:10]1[cH:11][c:12]([F:23])[c:13]([NH:18][S:19](=[O:20])(=[O:21])[CH3:22])[c:14]([CH:16]=[CH2:17])[cH:15]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 68453629[1-(3-Fluoro-4-methanesulfonylamino-5-vinyl phenyl)ethyl]carbamic acid tert-butyl ester

Product 1

HCID 68455310N-[4-(1-Aminoethyl)-2-fluoro-6-vinylphenyl]methanesulfonamide

Sources & evidence

ORD record
ord-674367f17f684f55a246a6d0000e1dc4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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