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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1670156Generated: October 31, 2026

HCID 57905822, compound → HCID 57905813, compound

https://huagongshe.com/reaction/1670156

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57905822HCID 57905822—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57905813HCID 5790581390%

Reaction Steps

To a solution of 4-(2-(2-Carboxy-ethyl)-3-{7-[5-(4-methyl-piperazine-1-carbonyl)-biphenyl-3-yl]-hept-6-ynyl}-phenoxy)-butyric acid (20 mg, 0.032 mmol) in MeOH (4 mL) was added 10% Pd/C (2 mg). The mixture was stirred for 4 h under hydrogen atmosphere at room temperature. The resulting suspension was filtered through Celite™ and concentrated under reduced pressure to afford the title compound. Yield: 90%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07989454B2
Source datasetuspto-grants-2011_08
ORD IDord-602a58c8f3e44be997b6c1eee334548e
Source noteuspto-grants-2011_08