Hydrochloric Acid → HCID 131727209, compound

Participants

Reaction Steps

Anhydrous HCl in dioxane (4N, 2.00 mL, 8.00 mmol, 165 eq) was added to tert-butyl 4-(2-(benzylamino)pyridin-4-yloxy)-3-fluorophenylcarbamate (0.020 g, 0.0489 mmol, 1.0 eq) and the reaction mixture was stirred at room temperature for 12 h. The reaction mixture was concentrated in vacuo to afford the title compound (0.017 g, 100%) a solid that was used without further purification. MS (ESI+) m/z 310 (M+H)+; HRMS (ESI+) calcd.: 310.1356. found: 310.1364.

Provenance & Evidence