Hydrogen Bromide → HCID 15986278, compound

Participants

Reaction Conditions

Reaction Steps

2-Chloro-5,10-dihydro-3,4,5,10-tetraaza-dibenzo[a,d]cyclohepten-11-one from Example 2 (400 mg, 1.62 mmol) was added to HBr (10 ml, 47% in water) and heated at 100° C. for 63 hours. The solution was cooled and diluted with EtOAc and NaOH (1M). The resultant precipitate was collected by filtration, washed with EtOAc and water and then dried under vacuum to give the title compound as a white solid (170 mg, 36%).

Provenance & Evidence