Hydrochloric Acid → HCID 67328829, compound

Participants

Reaction Steps

357.5 mg of 15 (0.97 mmol) prepared according to the procedure described in step 1 are taken up in a 25 mL round-bottomed flask and 6.3 ml of dioxane and 7.5 mL of a solution of hydrochloric acid in dioxane (4M) are added. The medium is stirred overnight at RT under argon. A precipitate forms which is drained and washed with isopropyl ether (15 mL) and dried under vacuum. 280 mg of expected product 16 (white solid) are obtained in hydrochloride form.

Provenance & Evidence