HCID 57617718, compound → HCID 57617755, compound

Participants

Reaction Steps

In an autoclave containing 270 mg of 21 (0.848 mmol), 20 mg of Pd/C (10%) and 5 mL of MeOH, hydrogenation is performed at 4 bar for 16 h at 20° C. After filtration of the catalyst on celite and evaporation of the solvent, 257 mg of expected product 23 are obtained, which product is used directly for the next stage.

Provenance & Evidence