HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenyloxolan-2-one → 3-Cyclohexyl-dihydro-furan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenyloxolan-2-one | HCID 23269 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Cyclohexyl-dihydro-furan-2-one | HCID 22013234 | 92.1% |
Reaction Steps
Stir a mixture of 3-phenyl-dihydro-furan-2-one (9.0 g), rhodium on carbone (5%, 3.62 g) and ethanol (220 mL) on a hydrogenation parr shaker at 60 psi, 60° C. for 18 hours. Remove the reaction from the parr shaker and filter the mixture through celite, concentrate the filtrate to afford 8.6 g (92%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07994176B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-1b2ddf76b64c4c319bb096b1f34f8ec6 |
| Source note | uspto-grants-2011_08 |