HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-hydroxyphenylacetate → HCID 14022788, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-hydroxyphenylacetate | HCID 28310 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 14022788 | HCID 14022788 | 99.7% |
Reaction Steps
Stir a mixture of (4-hydroxy-phenyl)-acetic acid ethyl ester (78.86 g), Rhodium on aluminum oxide (40%, 31.87 g) and ethanol (1 L) on a hydrogenation parr shaker at 60 psi, 60° C. for 18 hours. Remove the reaction from parr shaker. Filter the mixture through celite and concentrate the to afford 81.25 g (99%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07994176B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-db844cb313b944488c2dbe08b6d5c8aa |
| Source note | uspto-grants-2011_08 |