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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1670817Generated: November 1, 2026

Ethyl 4-hydroxyphenylacetate → HCID 14022788, compound

https://huagongshe.com/reaction/1670817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-hydroxyphenylacetateHCID 28310—
CatalystRhodiumHCID 23948—
SolventEthanolHCID 702—
ProductHCID 14022788HCID 1402278899.7%

Reaction Steps

Stir a mixture of (4-hydroxy-phenyl)-acetic acid ethyl ester (78.86 g), Rhodium on aluminum oxide (40%, 31.87 g) and ethanol (1 L) on a hydrogenation parr shaker at 60 psi, 60° C. for 18 hours. Remove the reaction from parr shaker. Filter the mixture through celite and concentrate the to afford 81.25 g (99%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07994176B2
Source datasetuspto-grants-2011_08
ORD IDord-db844cb313b944488c2dbe08b6d5c8aa
Source noteuspto-grants-2011_08