HCID 67212729, compound → HCID 67212437, compound

Participants

Reaction Conditions

Reaction Steps

To a solution 1-[3-(2,4-dichloro-phenyl)-2,6-dimethyl-pyrazolo[5,1-b]oxazol-7-yl]-butan-1-ol (0.700 g, 1.982 mmol) in CHCl3 (15 ml) is added manganese dioxide (3.45 g, 39.6 mmol); the reaction mixture is heated to 60° C. for 18 hours and filtered through Celite® (filter material) 521, washing through with chloroform (75 ml). The solvent is removed in vacuo to yield the title compound as a white solid; MS: m/z 351.04 [M+H]+

Provenance & Evidence