Bromide ion → 1-ethyl-4,4,6-trimethyl-7-[2-(2,2,2-trifluoro-ethoxy)-5-vinyl-phenyl]-3,4-dihydro-1H-quinolin-2-one
Reaction equation
[Br-:36].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH2:6]([CH3:7])[N:8]1[C:9](=[O:35])[CH2:10][C:11]([CH3:33])([CH3:34])[c:12]2[cH:13][c:14]([CH3:32])[c:15](-[c:18]3[cH:19][c:20]([CH:21]=[O:22])[cH:23][cH:24][c:25]3[O:26][CH2:27][C:28]([F:29])([F:30])[F:31])[cH:16][c:17]21.[CH3:37][P+:38]([c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1)([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1>>[CH2:1]=[CH:21][c:20]1[cH:19][c:18](-[c:15]2[c:14]([CH3:32])[cH:13][c:12]3[c:17]([cH:16]2)[N:8]([CH2:6][CH3:7])[C:9](=[O:35])[CH2:10][C:11]3([CH3:33])[CH3:34])[c:25]([O:26][CH2:27][C:28]([F:29])([F:30])[F:31])[cH:24][cH:23]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ab1eb15875184359b2d3032db26cc5a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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