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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1671692Generated: October 31, 2026

4-Fluorobenzaldehyde → 3-(3-Bromo-4-fluoro-phenyl)-3-chloro-2-oxo-propionic acid methyl ester

https://huagongshe.com/reaction/1671692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant3-Bromo-4-fluorobenzaldehydeHCID 173604—
ReactantMethyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoateHCID 57437156—
Product3-(3-Bromo-4-fluoro-phenyl)-3-chloro-2-oxo-propionic acid methyl esterHCID 64897869—

Reaction Steps

This compound was synthesised as 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester but using 3-bromo-4-fluorobenzaldehyde instead 4-fluorobenzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07994336B2
Source datasetuspto-grants-2011_08
ORD IDord-0fd2b62abc8440eba00f865aa61b3f91
Source noteuspto-grants-2011_08