Benzaldehyde → Methyl 3-chloro-2-oxo-3-phenylpropanoate

HRID 1671695Notes

Reaction equation

HRID 1671695 reaction equation
[CH3:1][O:2][C:3](=[O:15])[C:4](=[O:14])[CH:5]([Cl:13])[C:6]1[CH:11]=[CH:10][C:9](F)=[CH:8][CH:7]=1.C(=O)C1C=CC=CC=1.FC1C=CC(C=O)=CC=1>>[CH3:1][O:2][C:3](=[O:15])[C:4](=[O:14])[CH:5]([Cl:13])[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

4

Reactant 3

HCID 240BenzaldehydeHCID 680234-FluorobenzaldehydeHCID 57437156Methyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoate

Product 1

HCID 11769817Methyl 3-chloro-2-oxo-3-phenylpropanoate

Procedure

This compound was synthesised as 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester but using benzaldehyde instead 4-fluorobenzaldehyde.

Sources & evidence

ORD record
ord-3e5125a4675744e6b5032986012d2f5c
Source dataset
uspto-grants-2011_08
Patent number
US07994336B2

Reaction notes

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